PhD Student Position in Radiochemistry and Imaging Science: Harnessing cell signalling pathways to image protein degradation therapy in prostate cancer

veröffentlicht am: 09.01.2018

Institut, Seminar, Klinik / Institute, Department, Clinic

Department of Chemistry / Prof. Dr. Jason P. Holland

Abteilungsbeschreibung / Description of UZH unit

Our research lies at the interface of chemistry, biochemistry and translational molecular medicine. Chemical goals are to explore new radiolabelling methods and advance radiotracers for diagnostic imaging and/or radiotherapy. Molecular imaging goals focus on advancing positron-emission tomography/magnetic resonance imaging (PET/MRI) probes with an emphasis on using imaging science to measure dynamic changes in oncogenic signalling pathways in various cancers. Research is funded by the European Research Council, the Swiss National Science Foundation, Swiss Cancer Research (Krebsliga), and the UZH.
Please visit our website for more information:

Aufgabenbereich / Responsibilities

The appointed PhD student will conduct experimental and computational research on all aspects of radiotracer development. Specific areas include: radiochemistry with various nuclides, organic synthesis, coordination chemistry and biological studies in vitro and in vivo.

Anforderungen / Qualifications

Candidates must hold, or expect to have completed, a Master’s (MChem, MBiol, MSci or equivalent) degree in chemistry/biology/biochemistry prior to matriculation at UZH. Successful candidates will be ambitious, creative, and highly motivated, with an outstanding record of academic achievement as evidenced by:
- First class undergraduate/Bachelor’s and Master’s degrees (or equivalent qualifications) in chemistry/biology/biochemistry
- Academic awards at university level
- Experience in an experimental research laboratory

Ideal candidates will have a strong knowledge of fundamental chemistry (synthesis) and biochemistry. Practical experience in cell culture techniques, Western blots, PCR and protein expression is an advantage. The work involves handling human cells, radioactive materials and animals. Full training will be provided but prior experience is an advantage.

Sprachkenntnisse / Language requirements

Successful candidates will have excellent English language skills (written and oral). Ideal candidates will also be fluent in German.

Wir bieten / We offer

- Duration of the PhD position: maximum 4 years
- Academic stipends are commensurate with normal UZH regulations

Stellenantritt / This position opens on

August 2018

Bewerbungen / Application

Selection will be based solely on academic excellence and research potential. Short-listed applicants will be interviewed either in person or via video conference call. Please send applications as a single PDF file including a cover letter with a brief statement of motivation including past research experience/achievements (max. 2 pages), full CV (résumé), and the names and contact details of two referees to Prof. Jason P. Holland:

Prof. Dr. Jason P. Holland
Universität Zürich
Department of Chemistry
Winterthurerstrasse 190
8057 Zürich