PhD position in experimental cancer vaccination

veröffentlicht am: 29.01.2018

Institut, Seminar, Klinik / Institute, Department, Clinic

Department of Dermatology

Abteilungsbeschreibung / Description of UZH unit

Our research activities include basic, translational, and clinical research in the field of dermatology, including skin cancer, inflammatory skin disorders and allergy. In part, the research is focused on pathogenesis and diagnosis of disease, but also on therapy. Especially strong interested and expertise have developed in the field of immunotherapy of dermatological disorders. The department is accordingly well equipped for research utilising tissue cultures and small animals with methods of molecular biology, immunology, histology, as well as bioinformatics.

Aufgabenbereich / Responsibilities

The appointed PhD student will conduct experimental research on all aspects of cancer immunotherapy utilising a novel method called Photochemical internalisation (PCI), which combines vaccination and photodynamic therapy. The work is done in close collaboration with researchers from the Institute of Pharmaceutical Sciences at ETH Zurich who provide help in formulation of particulate vaccines, e.g. liposomes, and a biotech partner. The PhD student will be developing and testing vaccines in tissue cultures and in mice, and she/he will be using immunological and molecular assessment methods in vitro and in vivo, e.g. FACS, ELISA, immunohistochemistry, immunofluorescence microscopy, PCR and WB. The project is supported by the Swiss National Science foundation, University of Zurich, and a biotech partner.

Beschäftigungsgrad / Workload in %

100 %

Anforderungen / Qualifications

The candidate must hold a Master’s degree in biology, biochemistry, biotechnology, pharmacy or in an equivalent field. The candidate will be ambitious, creative, and highly motivated, with an outstanding record of academic achievement as evidenced by first class undergraduate/Bachelor’s and Master’s degrees, academic awards, experience in an experimental research laboratory, etc. Ideal candidates will have strong laboratory and organisation skills, have practical experience into some of the required methods, including cell culture techniques, for instance during an research internship. The work involves and animals. Full training will be provided but prior experience is an advantage.

Sprachkenntnisse / Language requirements

Successful candidates will have excellent English language skills (written and oral). Ideal candidates will also be fluent in German.

Wir bieten / We offer

- Duration of the PhD position (min 3 years)
- Salary is defined by normal UZH regulations
- Participation in PhD graduate student programmes (e.g. life science zurich)
- Participation at international scientific meetings and conferences

Stellenantritt / This position opens on

as soon as possible

Auskunft erteilt / More information

Prof. Dr. Pål Johansen, phone +41 44 255 86 16


Bewerbungen / Application

Selection will be based solely on academic excellence and research potential. Short-listed applicants will be interviewed either in person or via video conference call. Please send applications as a single PDF file including a cover letter with a brief statement of motivation including past research experience/achievements (max. 2 pages), full CV (résumé), and the names and contact details of two referees to Prof. Dr. Pål Johansen,

Prof. Dr. Pål Johansen
Universität Zürich
UniversitätsSpital Zürich, Dermatologische Klinik
Gloriastrasse 31
8091 Zurich